Amgen Bionext

Boston, Massachusetts

DSI played the key role in construction of the Amgen Bionext project as the hygienic process piping contractor and installer of all major process equipment. The facility manufactures the Amgen blockbuster drug Enbrel™, which has benefited the lives of millions of patients worldwide. Enbrel is prescribed for the treatment of five inflammatory conditions, including moderate to severe rheumatoid arthritis (RA), among others.

Amgen Bionext included four levels of process equipment, vessels and nine 20,000-liter Bioreactors. The project was accelerated to 16 weeks ahead of schedule with over 1 million safe work hours on-site.

DSI RolesProcess and Hygienic Contractor
Self-Performed WorkProcess Piping, Hygienic Piping, and Install Process Skids, Vessels and Equipment
Project size4 floors of process equipment and vessels
Total Volume$984 million
Highlights1 million safe work hours onsite (record in RI); DSI peaked at 215 craftsmen